دانشگاه آزاد اسلامی واحد تهران جنوب

صفحه اصلی / اولین کنفرانس ملی شیمی، نانو مواد، پلیمر- چالش ها و کاربردها

A Review of Novel Nanosystems in Enhancing Cell Death in Breast Cancer: Important Conclusions From Recent Advances

نویسندگان :

MohammadHossein Karami¹ Majid Abdouss² MohammadReza Kalaee³ Omid Moradi⁴

1- دانشگاه صنعتی امیرکبیر 2- دانشگاه صنعتی امیرکبیر 3- دانشگاه آزاد اسلامی واحد تهران جنوب 4- دانشگاه آزاد اسلامی واحد شهر قدس

کلمات کلیدی :

Cell Death،Breast Cancer،Nanocarrier،Drug Release

چکیده :

Nanotechnology-based drug delivery systems can reduce side effects, increase drug release time, and control drug release. Polymeric nanoparticles used as drug nanocarriers increase drug solubility and stability. Growing concerns about the safety of chemicals and additives have necessitated the use of bioactive substances. Drug concentration is an important factor in cytotoxicity studies as it can play a role in cell death and growth inhibition. Thus, beneficial substances released by nanocarriers remove negative and unstable substances from cells. Nanocarriers are designed for prolonged release of drugs at the cancer site, resulting in potent cytotoxicity. In the most recent study, nanocarriers are prepared by double emulsion methods that stabilize and fix the shape of the nanoparticles and also prevent the nanoparticles from accelerating during drug release in vivo. In this study, . Cytotoxicity investigated the effect of a newly developed nanocarrier on anti-inflammatory drug delivery to breast cancer cells(MCF-7).