دانشگاه آزاد اسلامی واحد تهران جنوب

صفحه اصلی / اولین کنفرانس ملی شیمی، نانو مواد، پلیمر- چالش ها و کاربردها

Cellulose-Coated Gold Nanoparticles: A Promising Nanostructure for Targeted Drug Delivery in Cancer Treatment

نویسندگان :

Amin Behzadnia¹ Neda Attaran kakhki² Mohammad Reza Kalaee³ Nafise MohammadMoradi⁴

1- دانشگاه آزاد اسلامی واحد تهران جنوب 2- دانشگاه آزاد اسلامی واحد علوم و تحقیقات 3- دانشگاه آزاد اسلامی واحد تهران جنوب 4- دانشگاه آزاد اسلامی واحد شهر قدس

کلمات کلیدی :

Cancer treatment،Cellulose coating،Drug delivery،Gold nanoparticles (GNPs)،Targeted therapy

چکیده :

Cancer is a formidable threat to human life, and conventional treatments often have limited efficacy and unwanted side effects. Therefore, scientists are exploring new methods of drug delivery for cancer treatment. Gold nanoparticles (GNPs), specifically, have gained attention due to their remarkable properties. In this study, we developed a novel GNP structure coated with cellulose as a carrier for delivering anticancer drugs to tumors. The Turkevich method was used to synthesize the GNPs, and their sizes were determined using transmission electron microscopy (TEM) and dynamic light scattering (DLS). UV-visible analysis measured the absorption of the samples. Fourier-transform infrared spectroscopy (FTIR) confirmed the successful conjugation of cellulose onto the GNPs. Our research successfully synthesized a promising nanostructure for future cancer treatment investigations. The cellulose-coated GNP structure serves as an effective carrier for delivering anticancer drugs to tumors. Combining the unique properties of GNPs with the biocompatibility and biodegradability of cellulose, this nanostructure shows potential for targeted drug delivery. Future studies will focus on evaluating stability, toxicity, and therapeutic efficacy in preclinical and clinical models. This research opens new avenues for innovative and efficient cancer therapeutics.